编辑:自杀的神经生物学:“自杀的大脑”

• ¹土耳其总理塔伊普Erdoğan大学,Turkiye
• ²土耳其总理塔伊普Erdoğan大学医学院Turkiye

(GMVs)前后电休克疗法(ECT)与MDD和青少年自杀意念。作者报道增加GMV正确的额上回、右侧颞回后等。他们还报道,frontal-temporal-precuneus结构的变化可能是一个潜在的导致青少年的抑郁和自杀症状(小李等)。在第六个研究中,李贾等人研究了焦虑之间的关联,抑郁和自杀行为的风险在中国医学院的学生。作者强调了焦虑和抑郁症状筛查的重要性在评估自杀行为的风险和减少焦虑除了抑郁症状在治疗(李贾等)。综述,Dobbertin等人评估当前的MRI结果研究自杀的大脑的神经影像学的变化及其相关性和实践。作者报道,有形态变化在大脑神经成像的研究中,特别是在frontolimbic网络,有证据指向认知功能恶化(Dobbertin等)。在第八条,户籍或等人研究了药物警戒的方法来评估自杀事件的发生引起的抗癫痫药物使用日本药品不良事件报告数据库。抗癫痫药物(AED)治疗后增加自杀是有争议的。作者建议,尤其是年轻女性使用多个抗癫痫药物应该警告自杀行为在第一个月的治疗(户籍或等)。 In the ninth article, Tsiouris and Flory compared the down-regulation of cyclic adenosine monophosphate levels in leukocytes of hibernating black bears with the findings of cyclic adenosine monophosphate reported in major depressive disorder. It has been reported in previous studies that cyclic adenosine monophosphate (cAMP) levels in lymphoblasts and leukocytes of patients with major depressive disorder (MDD) are downregulated compared to controls. Similarities have been noted between the neurobiological changes associated with MDD in humans and many conditions associated with mammalian hibernation. The authors noted that they resemble neurobiological findings associated with hypometabolism (metabolic depression) observed during mammalian hibernation and reported during MDD (Tsiouris and Flory). In the last study, da Silva Schmitz et al. sought an answer to the question of whether glutathione could be a biomarker for suicide risk in women 18 months after birth. In this study, it was concluded that there is a relationship between low glutathione levels in the postpartum period and suicide risk. The authors noted that glutathione may be a potential biomarker or etiological factor in women at moderate to high risk of suicide (da Silva Schmitz et al.).We would like to thank the Frontiers for their interest and support in the planning of our Research Topic. We would like to thank all the authors and referees who contributed to the preparation of the Research Topic.The preparation of the Research Topic was a long journey…. I would like to thank my esteemed colleagues, Professor E.Erdal Ersan and Dr.Hilario Blasco-Fontecilla, with whom we took part in this journey. I respectfully commemorate Professor Ghanshyam N. Pandey, with whom we were together at the beginning of the journey but passed away before our Research Topic was completed.The pandemic experience that affected our world during our Research Topic changed our lives. Then, a short time ago, the earthquake disaster that took place in our country, in Turkey, increased our suffering even more. I respectfully commemorate all the souls who passed away in both life events that created significant stress. Continuing to work, produce and contribute to science without losing hope and increasing solidarity despite all difficulties should be among our priorities... In conclusion, I think that the Research Topic provides the following: Determination of neurobiological risk factors for suicidal behavior will play an important role in the prevention of suicide, as well as in the regulation of treatment algorithms and in the follow-up of treatment.